String of bombings kill 101, injure 200 in Pakistan

QUETTA, Pakistan (Reuters) - At least 101 people were killed in bombings in two Pakistani cities on Thursday in one of the country's bloodiest days in recent years, officials said, with most casualties caused by sectarian attacks in Quetta.

The bombings underscored the myriad threats Pakistani security forces face from homegrown Sunni extremist groups, the Taliban insurgency in the northwest and the less well-known Baloch insurgency in the southwest.

On Thursday evening, two coordinated explosions killed at least 69 people and injured more than 100 in Quetta, the provincial capital of Balochistan, said Deputy Inspector of Police Hamid Shakil.

The first attack, in a crowded snooker hall, was a suicide bombing, local residents said. About ten minutes later, a car bomb exploded, they said. Five policemen and a cameraman were among the dead from that blast.

The attacks happened in a predominately Shia neighborhood and banned sectarian group Lashkar-e-Jhangvi claimed responsibility. The extremist Sunni group targets Shias, who make up about 20 percent of Pakistani's population.

Targeted killings and bombings of Shia communities are common in Pakistan, and rights groups say hundreds of Shia were killed last year. Militant groups in Balochistan frequently bomb or shoot Shia passengers on buses travelling to neighboring Iran.

The killers are rarely caught and some Shia activists say militants work alongside elements of Pakistan's security forces, who see them as a potential bulwark against neighboring India.

Many Pakistanis fear their nation could become the site of a regional power struggle between Saudi Arabia, source of funding for Sunni extremist groups, and Iran, which is largely Shia.

But sectarian tensions are not the only source of violence.

The United Baloch Army claimed responsibility for a blast in Quetta's market earlier in the day. It killed 11 people and injured more than 40, mostly vegetable sellers and secondhand clothes dealers, police officer Zubair Mehmood said. A child was also killed.

The group is one of several fighting for independence for Balochistan, an arid, impoverished region with substantial gas, copper and gold reserves, which constitutes just under half of Pakistan's territory and is home to about 8 million of the country's population of 180 million.

SWAT BOMBING

In another incident Thursday, 21 were killed and more than 60 injured in a bombing when people gathered to hear a religious leader speak in Mingora, the largest city in the northwestern province of Swat, police and officials at the Saidu Sharif hospital said.

"The death toll may rise as some of the injured are in critical condition and we are receiving more and more injured people," said Dr. Niaz Mohammad.

It has been more than two years since a militant attack has claimed that many lives in Swat.

The mountainous region, formerly a tourist destination, has been administered by the Pakistani army since their 2009 offensive drove out Taliban militants who had taken control.

But Talibans retain the ability to attack in Swat and shot schoolgirl campaigner Malala Yousufzai in Mingora last October.

A Taliban spokesman said they were not responsible for Thursday's bombing.

(Additional reporting by Jibran Ahmad in Peshawar, Pakistan; Writing by Katharine Houreld; Editing by Mark Heinrich and Jason Webb)

Read More..

US urges India, Pakistan to cool Kashmir tensions

WASHINGTON: The United States on Wednesday called on India and Pakistan to seek to cool tensions after Delhi accused the Pakistani army of beheading one of two Indian soldiers killed in Kashmir.

"Violence is not the answer for either country," State Department spokeswoman Victoria Nuland insisted.

"We've been counselling both governments to de-escalate, to work through this issue, to continue the consultations between them at a high level that we understand are ongoing now."

Pakistan has insisted no such incident had taken place in the disputed Kashmir region and suggested a UN inquiry be held.

But India has denounced the "inhuman" treatment of the two soldiers killed two days after a Pakistani soldier was also slain in the area.

Tensions have blown up along the Line of Control, the de facto border in Kashmir, over the past week with the two incidents again highlighting the six-decade long dispute over the Himalayan region.

Washington has been working through its embassies in both countries to calm tensions, and urging both governments to talk to each other, Nuland said.

The UN observer force in Kashmir is investigating an incident in which Pakistan said one of its soldiers was killed, UN spokesman Martin Nesirky told reporters in New York. But he added no complaint has been made about the clash in which India alleged one of its soldiers was beheaded.

Nuland said that if both sides "can work it out themselves, that's obviously best. If both parties were interested in support from the UN... we'd obviously support that as well."

- AFP/jc

Read More..

Maharashtra plans water trains for drought areas

MUMBAI: With the state witnessing an acute drought, the state government has decided to adopt unprecedented measures.

Anticipating that certain parts of Marathwada will go completely dry by March, the state government has drawn up a plan to transport water for drinking in railway wagons. At the state cabinet meeting on Wednesday, chief minister Prithviraj Chavan informed colleagues that initial discussions in this regard had been held with officials from Western Railway and Central Railway. Chavan further informed that the railway officials have agreed to provide three rakes for the purpose. He further said that the arrangement could provide means to transport five lakh litres of water to the drought-prone areas daily.

The total water storage in reservoirs in the Marathwada belt is barely 18%. Big dams like Ujni and Jayakwadi have almost gone dry.

Pressing the contingency plan, the state cabinet decided to provide a contingency grant of Rs 2 crore to collectors in drought-hit districts for emergency operations.

CM Prithviraj Chavan said the schemes have now been reserved for drinking water. The state has issued instructions asking authorities to prioritize completion of incomplete water supply schemes in drought-hit areas. Chavan has also issued directives asking officials to ensure that alternative means of employment are made available in the affected areas. The kharif crop production has been hit.

Read More..

Retooling Pap test to spot more kinds of cancer

WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported a tantalizing hint that one day, there might be.

Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.

How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.

In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.

This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.

"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.

But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.

The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.

"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.

"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.

But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.

More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.

Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.

The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.

So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.

The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.

Read More..

Arias Kissed New Beau Day After Killing Boyfriend

Jodi Arias drove to the home of her new romantic interest, kissed him, and laughed with his friends just 24 hours after she stabbed and shot her ex-boyfriend Travis Alexander to death, according to court testimony today.

Ryan Burns, whom Arias met in the spring of 2008, took the stand today at the start of the fourth day of testimony in the trial.

Arias, 32, is accused of murdering Alexander, 30, her one-time boyfriend whom she continued to sleep with occasionally. She claims he was abusive and she stabbed and shot him in self-defense. Alexander's body was riddled with 27 knife wounds including a slashed throat and a bullet wound to the head.

WATCH LIVE: Jodi Arias Murder Trial

Burns, who met Arias at a business conference, exchanged frequent long phone calls and online conversations with Arias before inviting her to come visit him in West Jordan, Utah, in June. Arias lived in California at the time.

Arias has confessed to driving to Alexander's home in Mesa, Ariz., where she killed him, and then to Burns' home in Utah. She arrived at Burns's home 24 hours after she was expected there, telling him that she got lost, drove the wrong way on a freeway for a few hours, fell asleep for awhile, and then got lost again, Burns testified today.

Jodi Arias Trial: Defense Claims Victim Was Sex Deviant Watch Video

Ariz. Woman Faces Death Penalty in Boyfriend's Slaying Watch Video

Photos of Key Players and Evidence in the Jodi Arias Murder Trial

She never told him that she had confronted Alexander with a knife or gun and ended up killing him just hours before their date.

When she arrived, the pair quickly got physical, he testified.

"We went back to my house. We talked for awhile, and agreed that we were going to watch a movie. At some point we were talking and we kissed. Every time we started kissing it got a little more escalated. Our clothes never came off, but at some point she was kissing my neck, I was kissing hers, but our clothes never came off," he said.

Burns said that both he and Arias stopped kissing at the time, though they again became physically involved later in the evening when Arias climbed on top of Burns and began kissing him. Burns said that they stopped kissing because he did not want her to "regret the visit" because of her Mormon beliefs about sex.

He also told prosecutors upon questioning that Arias was physically strong.

"She's very fit," he said, describing their encounter when she climbed on top of him. "She's very strong. She has close to a six pack (of abs)."

Prosecutors likely asked about the strength of Arias because in testimony Tuesday Maricopa County medical examiner Kevin Horn said Alexander was stabbed so forcefully that the blade chipped his skull and his neck was cut all the way back to the spinal cord.

Burns, who is also a Mormon, said he noticed two bandages on Arias's hand when she arrived at his house, which she told him she got when a glass broke at her place of employment, Margaritaville.

During her visit, the pair also went to a business meeting and went out with Burns' friends where Burns described Arias as acting "shy" and a "little awkward."

"She was fine, she was laughing about simple little things like any other person. I never once felt like anything was wrong during the day. With a crowd she was a little awkward in social areas, but one on one she was very talkative and excitable," he said.

Read More..

Venezuela court endorses Chavez inauguration delay

CARACAS (Reuters) - Venezuela's top court endorsed the postponement of Hugo Chavez's inauguration this week and ruled on Wednesday that the cancer-stricken president and his deputy would continue in their roles, despite a cacophony of opposition complaints.

Critics had argued the 58-year-old's absence from his own swearing-in ceremony on January 10 meant a caretaker president must be appointed. Chavez has not been seen in public nor heard from in almost a month following surgery in Cuba.

"Right now we cannot say when, how or where the president will be sworn in," Supreme Court Chief Judge Luisa Morales told a news conference.

"As president re-elect there is no interruption of performance of duties ... The inauguration can be carried out at a later date before the Supreme Court."

The decision opens the door in theory for Chavez to remain in office for weeks or months more from a Cuban hospital bed - though there is no evidence he is even conscious.

It leaves the South American country in the hands of Vice President Nicolas Maduro, as de facto leader of the government.

The opposition say that is a brazen violation of the constitution, and that Maduro should leave office on Thursday when the current presidential term had been due to expire.

They say National Assembly boss Diosdado Cabello, another powerful Chavez ally, should take over the running of the country while new elections would be organized within 30 days.

Maduro would be the ruling Socialist Party's candidate.

Government leaders insist Chavez, 58, is fulfilling his duties as head of state, even though official medical bulletins say he suffered complications after the surgery, including a severe lung infection, and has had trouble breathing.

His resignation or death would transform politics in the OPEC nation, where he is revered by poor supporters thankful for his social largesse, but denounced by opponents as a dictator.

RALLY PLANNED FOR THURSDAY

Moody's Investors Service warned on Wednesday that Venezuela's sovereign credit rating, already at junk status, faces short-term risks over any political transition.

Prices of Venezuela's widely traded bonds have soared lately on Chavez's health woes, but dipped this week as investors' expectations of a quick government change apparently dimmed.

The president has undergone four operations, as well as weeks of chemotherapy and radiation treatment, since being diagnosed with an undisclosed type of cancer in his pelvic area in June 2011.

He looked to have staged a remarkable recovery from the illness last year, winning a new six-year term at a hard-fought election in October. But within weeks of his victory he had to return to Havana for more treatment.

The government has called for a huge rally outside the Miraflores presidential palace in Caracas on Thursday, and allied leaders including Uruguay's Jose Mujica and Bolivia's Evo Morales have said they will visit - despite Chavez's absence.

Argentine President Cristina Fernandez, a close friend, has announced plans to visit Chavez in Cuba on Friday.

The unprecedented silence by Chavez, who is well known for his hours-long rambling speeches, has convinced many Venezuelans that his 14 years in power may be coming to an end.

Unlike after his previous operations in Cuba, no photographs have been published of him recuperating, and social media in Venezuela is buzzing with rumors he is on life support.

Cabello, the pugnacious head of the National Assembly, has repeatedly ruled out taking over as caretaker president to order a new presidential election, saying Chavez remains in charge.

"Tomorrow we will all go to the Miraflores palace," he told a televised Socialist Party meeting on Wednesday. "The people will be invested as president. We are all Chavez!"

(Additional reporting by Marianna Parraga and Diego Ore; Editing by Andrew Cawthorne)

Read More..

Yemen says US drone strikes to continue

SANAA: Yemen's national security chief said on Tuesday that US drone strikes against Al-Qaeda targets will continue as the two governments keep up their counter-terrorism cooperation.

"The Yemeni-American cooperation, including the use of friendly aircraft, will continue," Ali Hassan al-Ahmadi told reporters in Sanaa.

"Yemen is one of the countries that joined the international alliance to combat terrorism after the September 11," 2001 attacks on the United States, he said.

Washington has been stepping up its support for Yemen's battle against militants of Al-Qaeda in the Arabian Peninsula (AQAP), which it regards as the most active and deadliest franchise of the global jihadist network.

US drone strikes in Yemen nearly tripled in 2012 compared to 2011, with 53 recorded against 18, according to the Washington-based think tank New America Foundation.

At least 14 Al-Qaeda suspects have been killed in Yemen since December 24, when attacks by the unmanned aircraft on targets in Al-Bayda and the eastern Hadramawt province were stepped up.

AQAP took advantage of the weakness of Yemen's central government during an uprising in 2011 against now ousted president Ali Abdullah Saleh, seizing large swathes of territory across the south.

But after a month-long offensive launched in May last year by Yemeni troops, most militants fled to the more lawless desert regions of the east.

According to Ahmadi, "terrorist elements of around 13 nationalities took part in killing Yemenis during the past period and have destroyed Abyan province, especially (its capital) Zinjibar which was completely destroyed."

Around 170,000 people fled Abyan after the militants seized much of the province, he added.

- AFP/jc

Read More..

Highway authority files caveat in HC

NEW DELHI: Caught napping by GMR moving Delhi High Court to stop NHAI from encashing the performance security of Rs 260 crore after it served the termination notice on Kishangarh-Udaipur-Ahmedabad project, the highway authority has filed a caveat before the same court against GVK which has also served termination notice for Shivpuri-Dewas stretch. NHAI is also looking into the aspect of "debarring" GMR from future bidding.

Sources said that GVK has submitted at least Rs 100 crore as performance security to NHAI for the project. Though the authority has responded to the company's notice, there are chances of the firm exiting from this work. Officials said the viability of the project has "gone down on account of reduced traffic, increase cost of construction" and the company finding it difficult to raise equity. The NHAI has filed the caveat anticipating that GVK might follow GMR's footstep to get a stay on NHAI encashing the security amount.

Meanwhile, another infrastructure major IVRCL Group which had bagged 6-laning of Gundugolanu-Rajahmundry section on NH-5 in Andhra Pradesh, has also filed a caveat before Delhi High Court fearing NHAI might encash its security amount after it sought some clarification on "contract condition".

This case comes up for hearing on January 23.

Read More..

Report: Death rates from cancer still inching down

WASHINGTON (AP) — Death rates from cancer are continuing to inch down, researchers reported Monday.

Now the question is how to hold onto those gains, and do even better, even as the population gets older and fatter, both risks for developing cancer.

"There has been clear progress," said Dr. Otis Brawley of the American Cancer Society, which compiled the annual cancer report with government and cancer advocacy groups.

But bad diets, lack of physical activity and obesity together wield "incredible forces against this decline in mortality," Brawley said. He warned that over the next decade, that trio could surpass tobacco as the leading cause of cancer in the U.S.

Overall, deaths from cancer began slowly dropping in the 1990s, and Monday's report shows the trend holding. Among men, cancer death rates dropped by 1.8 percent a year between 2000 and 2009, and by 1.4 percent a year among women. The drops are thanks mostly to gains against some of the leading types — lung, colorectal, breast and prostate cancers — because of treatment advances and better screening.

The news isn't all good. Deaths still are rising for certain cancer types including liver, pancreatic and, among men, melanoma, the most serious kind of skin cancer.

Preventing cancer is better than treating it, but when it comes to new cases of cancer, the picture is more complicated.

Cancer incidence is dropping slightly among men, by just over half a percent a year, said the report published by the Journal of the National Cancer Institute. Prostate, lung and colorectal cancers all saw declines.

But for women, earlier drops have leveled off, the report found. That may be due in part to breast cancer. There were decreases in new breast cancer cases about a decade ago, as many women quit using hormone therapy after menopause. Since then, overall breast cancer incidence has plateaued, and rates have increased among black women.

Another problem area: Oral and anal cancers caused by HPV, the sexually transmitted human papillomavirus, are on the rise among both genders. HPV is better known for causing cervical cancer, and a protective vaccine is available. Government figures show just 32 percent of teen girls have received all three doses, fewer than in Canada, Britain and Australia. The vaccine was recommended for U.S. boys about a year ago.

Among children, overall cancer death rates are dropping by 1.8 percent a year, but incidence is continuing to increase by just over half a percent a year. Brawley said it's not clear why.

Read More..

James Holmes' Elaborate Booby Trap Plan Revealed

A gasoline-soaked carpet, loud music and a remote control car were part of an elaborate plan by accused Aurora gunman James Holmes' to trick someone into triggering a blast that would destroy his apartment and lure police to the explosion while he shot up a movie theater in Aurora, Colo., according to court testimony today.

FBI agent Garrett Gumbinner told a Colorado court about Holmes' complex plans to booby trap his apartment. Gumbinner said he interviewed Holmes on July 20, hours after he killed 12 and wounded 58 during the midnight showing of "The Dark Knight Rises."

"He said he rigged the apartment to explode to get law enforcement to send resources to his apartment instead of the theater," Gumbinner said.

Click here for full coverage of the Aurora movie theater shooting.

His plan failed to prompt someone into triggering the bombs.

Gumbinner said Holmes had created two traps that would have set off the blast.

The apartment was rigged with a tripwire at the front door connected to a mixture of chemicals that would create heat, sparks and flame. Holmes had soaked the carpet with a gasoline mixture that was designed to be ignited by the tripwire, Gumbinner said.

"It would have caused fire and sparks," the agent said, and "would have made the entire apartment explode or catch fire."

James Holmes: Suspect in Aurora Movie Theatre Shootings Back in Court Watch Video

Police Testify at Hearing for Accused Colorado Gunman Watch Video

New Jersey Missing Teens: Body Pulled From Lake Watch Video

Holmes had set his computer to play 25 minutes of silence followed by loud music that he hoped would cause a disturbance loud enough that someone would call police, who would then respond and set off the explosion by entering the apartment.

Gumbinner said Holmes also told him he rigged a fuse between three glass jars that would explode. He filled the jars with a deadly homemade chemical mixture that would burn so hot it could not be extinguished with water.

Holmes set a second detonation system outside the building, the agent said.

Holmes, Gumbinner said, rigged one of the triggering devices, called a "pyro trip box" with a remote control. He then took the remote control outside and placed it on top of a white trash bag near the apartment building.

Next to the remote, Holmes placed a remote control car. Inside the trash bag, he put a portable stereo set to play 40 minutes of silence, followed by loud music, the agent said.

The plan, Gumbinner explained, was for someone to hear the music and be drawn to the remote control car with what appeared to be the remote control lying next to it. When that person picked up the remote to activate the car, he or she would have unknowingly triggered the explosion in the apartment.

Holmes also left rows of white powder on the floor, which Gumbinner said was ammonium chloride. The powder, Gumbinner believes, was meant "to scare us" and would have created a large amount of smoke if it had ignited.

Prosecutors showed several photographs of the devices in court.

Holmes legally bought thousands of bullets, four guns and chemicals, months before prosecutors say he opened fire on a crowded movie theater, an ATF agent testified today.

Click here for more details on his deadly arsenal.

Earlier in the day, prosecutors played two 911 calls in court, including the very first call from movie goer Kevin Quinonez as the shooting was still underway.

At least 30 rapid-fire gunshots could be heard in the background of the 27-second call, along with screaming.

"Gunshots?" Quinonez can be heard saying.

The dispatcher pleads with Quinonez to give the theater address, but the sound of gunshots and chaos drowns him out.

Read More..